If you are looking for a delightful, creamy comfort food that combines tender chicken, earthy mushrooms, and a rich plant-based cheese sauce (plant-based), this Chicken Tetrazzini Casserole is the perfect recipe to try. Packed with flavor and incredibly satisfying, this dish offers a heartwarming twist on a traditional classic that you will want to make over and over again, especially when you crave a creamy pasta bake that’s bursting with flavor and texture.

Why You’ll Love This Recipe

Ultimate Comfort Food: Creamy, cheesy, and full of tender chicken and mushrooms that warm the soul.
Simple Ingredients: Easy-to-find kitchen staples combine to create an impressive dish with minimal effort.
Family Friendly: Pleases picky eaters and can be effortlessly doubled for crowd-pleasing meals.
Make-Ahead Friendly: Perfect for preparing in advance and baking when you’re ready.
Customizable Delight: Easily adapted to fit different dietary needs or flavor preferences.

Ingredients You’ll Need

This recipe relies on a few key ingredients that work harmoniously to deliver creamy texture, rich flavor, and a golden finish. Each component plays a crucial role in building the layers of this delicious chicken tetrazzini casserole.

Cooked Chicken: Shredded or diced tender chicken adds protein and heartiness.
Spaghetti Pasta: The classic base that absorbs the creamy sauce beautifully.
Mushrooms: Provide an earthy, umami flavor and a meaty texture.
Plant-Based Cheese Sauce: The star of the casserole, creating rich creaminess and great meltability.
Onion and Garlic: Adds depth and aromatic notes, enhancing every bite.
Vegetarian Worcestershire Sauce (natural): Gives an umami punch without overpowering the dish.
Apple Cider Vinegar (natural): Provides a subtle tang to balance the richness.
Natural Gelling Agent: Used to achieve perfect sauce consistency and creaminess.
Smoked Turkey Bacon: Adds a smoky, crispy accent that contrasts beautifully with the creamy elements.
Plant-Based Milk: Keeps the sauce smooth and luscious without heaviness.
Fresh Parsley: Brightens the casserole visually and flavor-wise.

Variations for Chicken Tetrazzini Casserole

One of the best things about this Chicken Tetrazzini Casserole is how easy it is to personalize. You can adjust the recipe to match your pantry, taste preferences, or nutritional needs without losing any magic.

Swap the Pasta: Use penne, rigatoni, or gluten-free pasta for a different texture or dietary adaptation.
Vegetarian Version: Replace chicken with chickpeas or sliced seitan for a plant-based protein option.
Extra Veggies: Add peas, spinach, or bell peppers to boost color and nutrients.
Spice it Up: Toss in red pepper flakes or smoked paprika for a warming kick.
Cheese Variations: Experiment with different plant-based cheese sauces like mozzarella or cheddar styles.

Easy Chicken Tetrazzini Casserole Recipe to Try

How to Make Chicken Tetrazzini Casserole

Step 1: Prepare the Pasta and Chicken

Cook spaghetti according to package instructions until al dente, then drain and set aside. Meanwhile, shred cooked chicken into bite-sized pieces, ensuring it’s tender and easy to mix.

Step 2: Sauté the Vegetables and Smoked Turkey Bacon

In a large skillet, cook diced smoked turkey bacon until crispy, then remove and set aside. In the same pan, sauté chopped onions and garlic until fragrant and translucent. Add sliced mushrooms and cook until softened and golden.

Step 3: Make the Creamy Plant-Based Cheese Sauce

Combine plant-based milk, plant-based cheese sauce, apple cider vinegar (natural), vegetarian Worcestershire sauce (natural), and natural gelling agent in a saucepan. Heat gently while whisking until the sauce thickens into a luscious, creamy texture that will coat the pasta perfectly.

Step 4: Combine and Assemble the Casserole

In a large mixing bowl, combine cooked spaghetti, shredded chicken, sautéed vegetables, smoked turkey bacon, and creamy cheese sauce. Mix everything thoroughly to ensure every bite is flavorful and coated with sauce.

Step 5: Bake to Golden Perfection

Transfer the mixture into a greased casserole dish and top with extra plant-based cheese sauce for a golden crust. Bake at 350°F (175°C) for 25 to 30 minutes until bubbling and slightly browned on top.

Pro Tips for Making Chicken Tetrazzini Casserole

Use Day-Old Chicken: Cooked chicken from a previous meal adds fantastic texture and flavor without extra prep.
Don’t Overcook Pasta: Al dente pasta keeps the casserole from becoming mushy after baking.
Toast Mushrooms Well: Browning mushrooms deeply enhances their earthy flavor and reduces excess moisture.
Mix Sauce Well: Whisk sauce continuously when heating to avoid lumps and achieve a smooth texture.
Let It Rest: Allow the casserole to sit 5 minutes after baking for flavors to set and easier serving.

How to Serve Chicken Tetrazzini Casserole

Garnishes

A sprinkle of freshly chopped parsley or thyme adds a fresh, herbaceous pop that brightens the casserole beautifully.

Side Dishes

Serve with a crisp green salad dressed lightly in lemon and olive oil or roasted vegetables to balance the richness of the casserole.

Creative Ways to Present

For individual servings, bake the casserole in small ramekins or muffin tins for fun, personal portions that look impressive and are easy to serve.

Make Ahead and Storage

Storing Leftovers

Keep leftover Chicken Tetrazzini Casserole in an airtight container in the refrigerator for up to 3 days, ensuring flavors meld while staying fresh.

Freezing

This casserole freezes well place portions in freezer-safe containers and freeze for up to 2 months to enjoy anytime convenience.

Reheating

Reheat leftovers gently in the oven at 325°F (165°C) to preserve the creamy texture, or microwave with a splash of plant-based milk to restore moisture.

FAQs

Can I use another type of pasta for Chicken Tetrazzini Casserole?

Absolutely! While spaghetti is classic, penne, rigatoni, or any short pasta works well and can change the texture to your liking.

Is this recipe suitable for dairy-free diets?

Yes, by using plant-based cheese sauce and milk, this casserole is completely dairy-free and still rich in flavor and creaminess.

How can I add more vegetables to this dish?

Feel free to mix in spinach, peas, or diced bell peppers during the sauté step for added nutrients and color.

Can I prepare the casserole ahead of time?

Yes, assemble the casserole fully, cover tightly, and refrigerate up to 24 hours before baking to save time on serving day.

What can I serve alongside Chicken Tetrazzini Casserole?

A fresh salad or steamed greens complement the rich casserole perfectly by adding a crisp texture and balancing flavors.

Final Thoughts

Chicken Tetrazzini Casserole is a soul-satisfying meal full of creamy, savory flavors that bring everyone around the table for seconds. Easy to customize, make-ahead friendly, and packed with comforting ingredients, this recipe is one you will return to time after time. Grab your ingredients and dive into the cozy goodness of this delicious casserole soon!

Chicken Tetrazzini Casserole

Author: Marcus
Total Time: 55 minutes
Yield: 6 servings 1x
Diet: Dairy-Free

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Description

Chicken Tetrazzini Casserole is a creamy, comforting dish featuring tender chicken, earthy mushrooms, and a rich plant-based cheese sauce. This flavorful pasta bake combines simple ingredients to create a heartwarming meal perfect for family gatherings or make-ahead dinners. Enhanced with smoked turkey bacon for a smoky crunch and fresh parsley for brightness, this casserole is customizable and satisfying for all tastes.

Instructions

Prepare the Pasta and Chicken: Cook spaghetti according to the package instructions until al dente, then drain and set aside. Shred or dice cooked chicken into bite-sized pieces, ensuring tenderness for easy mixing.
Sauté the Vegetables and Smoked Turkey Bacon: In a large skillet, cook diced smoked turkey bacon until crispy, then remove and set aside. Using the same pan, sauté chopped onions and minced garlic until fragrant and translucent. Add sliced mushrooms and cook until softened and lightly golden.
Make the Creamy Plant-Based Cheese Sauce: In a saucepan, combine plant-based milk, plant-based cheese sauce, apple cider vinegar (natural), vegetarian Worcestershire sauce (natural), and natural gelling agent. Heat gently while whisking continuously until the sauce thickens into a smooth, creamy texture that will coat the pasta evenly.
Combine and Assemble the Casserole: In a large mixing bowl, mix cooked spaghetti, shredded chicken, sautéed vegetables, smoked turkey bacon, and the creamy cheese sauce. Stir thoroughly to ensure even coating and flavor distribution.
Bake to Golden Perfection: Transfer the mixture into a greased casserole dish. Spread additional plant-based cheese sauce on top for a golden crust. Bake in a preheated oven at 350°F (175°C) for 25 to 30 minutes, or until the casserole is bubbly and slightly browned on top.

Notes

Use day-old cooked chicken to enhance flavor and texture.
Do not overcook pasta to prevent mushy casserole; al dente is ideal.
Toast mushrooms thoroughly to deepen flavor and reduce moisture.
Whisk sauce continuously while heating to avoid lumps and achieve smoothness.
Let the casserole rest for 5 minutes after baking for better flavor setting and easier serving.

Prep Time: 20 minutes
Cook Time: 35 minutes
Category: Main Course
Method: Baking
Cuisine: American